Hello! I know this is an older thread, but I think it may just be the most complete out there and I wanted to share what seems to have happened in my case. I'm also a 37 year-old female but I've only been vaping for about 7 months and mostly menthol flavours.
I had a mild cold a couple of weeks ago. On the tail end of it I began having palpitations that developed over ~10 days into a permanent bounding pulse (which I felt from the base of the neck all the way into the abdomen). In parallel, there was central chest pressure/pain/dull ache that radiated occasionally and randomly with stabbing pains through the chest and into the upper back. Sometimes I felt this "gurgling" that seemed to suggest turbulent flow through the heart valves. No shortness of breath, however.
I proceeded to freak out because I have had an extensive bilateral pulmonary embolism (PE) a few years ago. Two trips to the ER and a red herring (GERD/reflux) later, I am sure it was a reaction to something in the juice I'd been vaping (VanGo's "Frozen Ophelia" - 70% VG, menthol, cactus, kiwi, strawberry, pineapple). On the first ER visit, seeing that my vitals + oxygen saturation were fine sufficed because I could assess my risk of another PE as low and I left on my own, but by the second visit the reflux hypothesis had been disproved, I was miserable and in constant pain. EKG, cardiac enzymes and chest Xray were fine, which I found somewhat unsettling (this left it to either anxiety - which I'd never experienced in this way and doubted greatly - or something truly horrible like aortic dissection).
I finally figured to change the juice flavour profile and go back from the iJoy Capo100 I'd been using to my little Aspire Breeze; what do you know - the pain subsided considerably. The next day went virtually pain-free until I decided to test this (I know... it's just that I'd never had a sensitivity/allergic response to any substance, plus I'd vaped the same juice before at twice my current nicotine level). Three puffs of "Frozen Ophelia" resulted in a full hour of pain just like before. I don't think it was the VG or PG as they are at similar concentrations in the coffee-flavoured juice I vape now, but probably one of the flavourings or (very sad if so) the menthol.
I'll always recommend getting a chest pain checked, but sometimes, even if the question is weird like this combo of symptoms, the answer might be simpler and less expensive...