I explain build/resistance/vapor and nicotine to people by comparing it to alcohol. Higher nic = higher alcohol. If a MTL clearo with a 2.2 Ohm coil is a coffee stirrer sippy straw, and a wide open RDA with a .15 Ohm coil is a funnel... well, you can get the same effect using bourbon with the sippy straw as you could guzzling beer through a funnel. Likewise, you'd make yourself sick or dead pouring bourbon through a funnel, and just frustrate yourself with beer and a sippy straw. In the middle are the schnapps and cocktails... go ahead and drink those through a regular straw
comparable to something like the Kanger Subtank or Aspire Atlantis. Likewise, use higher nic in the MTL tank, much lower nic in the wide open RDA with the low build. Use middling nic in the middling tanks with the middling builds.
If you're just trying to get rid of nic cravings, consider that each cigarette delivers about 1 mg nicotine. Vapor is metabolized at about 75-80% the efficiency of combustible tobacco. If you smoked a pack a day, you'll want to vape about 1 ml of 24 nic, 2 ml of 12 nic, 4 ml of 6 nic, and 8 ml of 3 nic to get a comparable amount of nicotine. Any more than that, and you'll likely experience some symptoms...