Anyone know if there is any truth behind this? What it is in cigarettes that might reduce migraine headache pain and frequency? Besides nicotine. I am more interested in any other chemical in cigarettes that might have that effect that isn't present in vape juice. A friend of mine was saying smoking helps her headache, but you can get nicotine from vaping. I'm trying to get her to switch. She already smokes. I won't go into her medical history, but she is seeing a doctor already. Any ideas?