For a regulated mod, I find that big fat Ni80 coils always require to use the preheat feature of the mod because else the ramp up will tend to be too slow, which kills the flavor. There are plenty of regulated mods that have the feature, but only a handful are designed in such a particular way that all of the following criteria are met with no exception:
1. The ability to use a custom power curve for preheat. A lot of modern advanced mods can do this.
2. The numbers that make up the custom power curve are percentages placed on a timeline. Almost all mods that can do a custom power curve are using wattages instead of are using percentages... percentages = the mod itself scales the power curve automatically conveniently for you so, each time when you change the wattage setting on the mod, you don't need to keep manually editing the wattages that make up the curve, i.e. the mod handles this all perfectly on-the-fly so you don't have to.
3. The power output capability is sufficient to accomodate the high wattage vaping needs that are typically associated with using big fat coils.
4. The battery life is still reasonable enough despite driving into high wattage vaping territory.
5. The ease-of-use is still suprisingly great in addition to all of the above mentioned criteria.
So the Wismec Reuleaux RX300 (with ArcticFox firmware, in cohort with the accompanying NFE Tools software that you can run on a Windows PC) has my preference for this. Below is a pic of my 12ply .4×.1 Ni80 / 40g Ni80 staple coils (.11 ohms dual coil build) in my 24mm Goon that I vape at 170 watts, but you could always decide to grab the 25mm Goon that I also own.