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Are Metals Emitted from Electronic Cigarettes a Reason for Health Concern? A Risk-Assessment Analysis of Currently Available Literature
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454963/
Methods: Two studies were found in the literature, measuring metals emitted to the aerosol from 13 EC products.
We estimated that users take on average 600 EC puffs per day, but we evaluated the daily exposure from 1200 puffs.
Estimates of exposure were compared with the chronic Permissible Daily Exposure (PDE) from inhalational medications defined by the U.S. Pharmacopeia (cadmium, chromium, copper, lead and nickel), the Minimal Risk Level (MRL) defined by the Agency for Toxic Substances and Disease Registry (manganese) and the Recommended Exposure Limit (REL) defined by the National Institute of Occupational Safety and Health (aluminum, barium, iron, tin, titanium, zinc and zirconium).
Results: The average daily exposure from 13 EC products was 2.6 to 387 times lower than the safety cut-off point of PDEs, 325 times lower than the safety limit of MRL and 665 to 77,514 times lower than the safety cut-off point of RELs.
Only one of the 13 products was found to result in exposure 10% higher than PDE for one metal (cadmium) at the extreme daily use of 1200 puffs.
5. Conclusions
In conclusion, the levels of metals emitted to the EC aerosol, as found in currently available literature, are unlikely to generate significant adverse health effects for smokers switching to EC use. However, discrepancies between products indicate that standards in product quality should be implemented in order further reduce unnecessary exposure to metals.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454963/
Methods: Two studies were found in the literature, measuring metals emitted to the aerosol from 13 EC products.
We estimated that users take on average 600 EC puffs per day, but we evaluated the daily exposure from 1200 puffs.
Estimates of exposure were compared with the chronic Permissible Daily Exposure (PDE) from inhalational medications defined by the U.S. Pharmacopeia (cadmium, chromium, copper, lead and nickel), the Minimal Risk Level (MRL) defined by the Agency for Toxic Substances and Disease Registry (manganese) and the Recommended Exposure Limit (REL) defined by the National Institute of Occupational Safety and Health (aluminum, barium, iron, tin, titanium, zinc and zirconium).
Results: The average daily exposure from 13 EC products was 2.6 to 387 times lower than the safety cut-off point of PDEs, 325 times lower than the safety limit of MRL and 665 to 77,514 times lower than the safety cut-off point of RELs.
Only one of the 13 products was found to result in exposure 10% higher than PDE for one metal (cadmium) at the extreme daily use of 1200 puffs.
5. Conclusions
In conclusion, the levels of metals emitted to the EC aerosol, as found in currently available literature, are unlikely to generate significant adverse health effects for smokers switching to EC use. However, discrepancies between products indicate that standards in product quality should be implemented in order further reduce unnecessary exposure to metals.