1. What version of Escribe and Firmware do you have? The latest test firmware is "Firmware 2016-02-29 EScribe 1.0.42". The newest recommended is "Firmware 2015-10-21 EScribe 1.0.35.2" You can find the Escribe version in the help tab at the top under about. The firmware version can be seen in the device manager in the lower right corner. You can download either one
here.
PS I'm running the latest test firmware and like it alot.
Take a look at this thread to see all the new options the test firmware offers. Here's the
link.
2. I thought the Efusion came pre-configured from the factory, Doesn't it? If so, I'm not sure why you are trying to run the .Ecig file. It's neither here or there since you should be able to if the mood strikes. I would suggest making sure you have the latest version of Escribe and firmware installed first and then go from there.
Cheers,
Steve