It seems to me that with DIY I get larger recipe flexibility using PG based flavorings. If mixing higher nicotine level recipes using PG based nic., the amount of added PG based flavoring can be limiting should one desire 80%VG in the finished juice. Some mixers sometimes use an amount of PG flavorings which, with lesser nic. levels, can also make it difficult to achieve 80%VG.
You may wish to "do the numbers" to determine if PG based nic. will work for you.
Ron
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"Persuade thyself that imperfection and inconvenience are the natural lot of mortals, and there will be no room for discontent, neither for despair."- Ieyasu Tokugawa