Everyone's tolerance is different. So is everyone's susceptibility to addiction. I'd venture to say based on life experience, no your body won't 'reset', it will still build a tolerance. 3 days a week is still pretty regular. I've dated people that smoked one or two cigs then not pick up another for 6mo or a year and a half. Nicotine 'buzz' is hardly worth the trouble imo. Maybe a step above a 'sugar buzz'. This sounds like snorting pixie sticks (showing my age lmao) but that's what I'm getting from it.
Going back to my days of dipping, yea I got a buzz from it the first time, maybe the second. It lasted a whopping 3-4min. It's like anything, even drinking. Slam your first beer or shot and you'll probably get a slight buzz. Have a few beers only one evening a week, the body will build a tolerance. You can imagine the tolerance built doing so 3-4 days a week.
Chasing a buzz is a dangerous game, it will inevitably require more and more. It goes from just a beer to a shot with a beer back to lining shots up to keg stands, funneling and butt chugging. Then oops, it was too much and you're on the 9pm news. It sounds like the sort of behavior I would advise against. Same thing with vaping, trying all sorts of ignorant things to get to the next 'level'.
Getting your body used to something a few days steady, then a few days off you're repeatedly putting it through a shock process. Even mild things like caffeine can have ill withdrawal effects in the form of mild irritation and headaches. I just don't get the payout of a 'nic buzz' and with the mindset demonstrated on the goal - whatever floats your boat I guess. I don't see any reward in this venture, only problems. If there were 'safe' ways to get high then people wouldn't get addicted but that's usually where it ends up.
I've drank, I've gotten drunk off my ass and passed out. Those events have happened maybe once a year or every couple of years, aside from that I'm not an alcoholic. I don't 'have' to have a drink, perfectly fine going months without a drink. I'm fine with a casual drink in a social setting. Looking at the past 18-24mo, I think I've had a single wine cooler and maybe a cocktail. If I were doing it every week or few days a week I'm pretty sure I'd 1) build a tolerance and 2) develop a dependency. Some of it is mental and you're already going there planning xyz days of the week to do this, so those few days your mind is already looking forward to a form of chemical abuse. The drinking is just an example, fill in the blanks with whatever you wants - drugs, alcohol, glue, nitrous, nicotine.