it will work, don't think it won't.. but as you tinker with your flavoring, you will be able to pick things apart..
once you reach that level.. from there you can decide if to improve it for a main taste in your juice, or..
decide to make it a minor attraction..
for my version of a "ry4":
first, i pick the tastest tobacco as the main player..
then 2 more... for body and depth..
i have used the lightest, and the darkest and in between..
as you go thru the web hunting.. you might even see things like:
tobacco brown or tobacco light
a brown tobacco would be like the nutty 555, or even a heavy tobacco/cigar like tuscan reserve
a light would be your oryental or english tobacco..
then you need to think on your vanilla's or creams..
how heavy or light do you want it? there is nothing stopping you.. either way is right..

do you want it spicy, plain, vanilla-ish, barely noticeable, or heavy?
and your sweets..
i always pair my vanilla with a half dose of caramel/butterscotch.. or an equal of both..
so to look at an ry4 like this, my version:
tobaccos (going for a bold ry4)
1.5% fa burly (dark)
1% fa max (medium)
.75% fa shade (for the wrapping, light)
vanilla/cream (since my tobacco is bold.. heavy cream is out!)
.75% fa irish cream (oh yes, i went there! light vanilla with that tiny bit of mint)
.5% fa vanilla tahiti (for the nut! with cream..)
now at this point, you can decide if you want it an alcohol flavored ry4 or not..
if so, i have better luck with the bourbons and rums from tfa..
1% tfa bourbon
.5% tfa brandy (or go crazy and try .35% tfa orange brandy)
smoother or burnt sugar effect
.25% fa butterscotch
and your additives..
.25% mts vape wizard (to smooth, not smother!)
.5% apple cider vinegar (for dark tobaccos, blender, smoother and enhancer)
and finally.. if i want good luck, i might drop .25% fa black cherry
or.. if I want a tastier vanilla-ish.. i would go as far as 2-2.5% vanillin..
thats about it