How Heart Disease Affects the Brain
By Chauncey Crandall, M.D.
The brain requires a lot of oxygen to stay healthy. If atherosclerosis limits the blood flood to the brain, a condition called “hypoxia” can occur.
Although the relationship between Alzheimer’s disease and hypoxia is not completely understood, some researchers believe that hypoxia may trigger a cascade of actions that causes the plaques and tangles of Alzheimer’s.
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Along with hypoxia, there are two other conditions found in the brains of Alzheimer’s patients — inflammation and oxidation (or oxidative stress) — that are also associated with heart disease.
When chronic inflammation occurs inside the body, for example as a result of high blood pressure, it causes a toxic situation that can trigger the development of heart disease.
Oxidation is the natural byproduct of metabolism — the transformation of the food we eat into energy. But this cellular response is also believed to be the root cause of the aging process, much as when iron oxidizes and the resulting rust corrodes a car.
When this process occurs in the body, it can damage the coronary arteries. And when oxidation occurs in the brain, it causes brain cells to die, which is one of the hallmarks of Alzheimer’s.
By Chauncey Crandall, M.D.
The brain requires a lot of oxygen to stay healthy. If atherosclerosis limits the blood flood to the brain, a condition called “hypoxia” can occur.
Although the relationship between Alzheimer’s disease and hypoxia is not completely understood, some researchers believe that hypoxia may trigger a cascade of actions that causes the plaques and tangles of Alzheimer’s.
Special: Over 50? Serious Brain Nutrition Combats Scary Mental Decline
Along with hypoxia, there are two other conditions found in the brains of Alzheimer’s patients — inflammation and oxidation (or oxidative stress) — that are also associated with heart disease.
When chronic inflammation occurs inside the body, for example as a result of high blood pressure, it causes a toxic situation that can trigger the development of heart disease.
Oxidation is the natural byproduct of metabolism — the transformation of the food we eat into energy. But this cellular response is also believed to be the root cause of the aging process, much as when iron oxidizes and the resulting rust corrodes a car.
When this process occurs in the body, it can damage the coronary arteries. And when oxidation occurs in the brain, it causes brain cells to die, which is one of the hallmarks of Alzheimer’s.