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Folate Warning [Part 3] - "Fix" MTHFR
This email covers ...- How to get all of your folate from food
- Some steps to ensure that you recycle folate well
- A simple "fix" for a defective MTHFR enzyme (without using folate)
So if your folate is not so low that you need a supplement to raise it quickly, you might want to consider getting all of your folate from food and also make sure that you are recycling your folate well.
Your folate level and how well you recycle it could be described collectively as your "folate status".
An optimal way to support your folate status (and the methylation cycle that depends on it) could include the following steps:
- Eat folate-rich foods like beef liver (the only source of methylated folate), legumes (especially lentils), asparagus, avocado, beets, broccoli, Brussels sprouts, papaya, citrus fruit, and leafy greens.
- Test your blood folate level (and ideally all of your B vitamins) to see if you're getting enough from your diet.
- Test all of the genes in your folate cycle (about 5 genes), and ideally also in your methylation cycle (about 5 more genes), and nutrient transport genes, to spot which of your genes might need extra support to run the folate and methylation cycles and other biological processes that require nutrients that you might not absorb well.
There is also a step (an enzyme) in the methylation cycle that keeps B12 methylated and reduced.
The folate cycle, the B12 cycle, and the methylation cycle involve more than just the MTHFR gene/enzyme.
I repeatedly emphasize because to have good folate function and good methylation in the body, just focusing on MTHFR is often not enough.
Aside from the risks of just taking a lot of folate as a way of dealing with a defective MTHFR enzyme, that just bypasses the MTHFR enzyme (and the other enzymes in the folate cycle) and even potentially further downregulates MTHFR activity.
Rather than trying to bypass enzymes in the folate cycle and taking on the risks associated with overdoing folate, there is another option ...
... you can actually help the MTHFR enzyme work better
All you have to do is ensure that you are getting enough vitamin B2 (riboflavin).
Vitamin B2 converts to the cofactor that the MTHFR enzyme needs to function.
A defect in the MTHFR enzyme reduces its affinity for its B2-based cofactor, but if you supply more of MTHFR's cofactor, MTHFR works better.
So far, all of my clients have been quite deficient in B2, so it seems that B2 deficiency is prevalent in people with health challenges.
And one of the effects of B2 deficiency is to reduce the function of the MTHFR enzyme, even if you don't have a genetic defect in MTHFR.
Did you catch that?
If you are B2 deficient, your MTHFR enzyme might not be working well, even if you don't have any of the MTHFR genetic defects.
And if you do have a defective MTHFR, B2 deficiency will definiltely worsen your MTHFR function.
By the way, the B2-based cofactor for the MTHFR enzyme is flavin adenine dinucleotde (FAD), and FAD is also necessary for many other important enzymes like glutathione reductase that recycles oxidized glutathione and monamine oxidase that helps to clear histamine (as well as neurotransmitters like serotonin and dopamine).
One of the subscribers to this newsletter told me that she had a "major turn around in my GI issues" after she implemented my suggestion of taking B2.
Perhaps her gut started clearing histamine in the gut faster, or more quickly clearing excess serotonin in the gut (a mediator of inflammation in the gut) because clearing histamine or serotonin involves B2 / FAD as the cofactor for the monamine oxidase enzyme.
FAD is also essential for transporting electrons in mitochondrial energy production, especially electrons that come from metabolizing fat.
High-fat diets (e.g. keto) require more FAD to process the elecrons coming from fat, so it's somewhat common for people on ketogenic diets to become deficient in B2 / FAD if they are not aware that they may need to take extra B2.
Some people do not activate B2 very well, so if you can get it in the activated riboflavin-5-phosphate (R5P) form, that might work better for you.
Unlike supplementing with folate, supplementing with riboflavin poses little or no health risk.
I have never seen any information about riboflavin toxicity, so it seems that no toxic dose of B2 has ever been identified.
To summarize ...
- Some of the richest food sources of folate include beef liver (the only source of methylated folate), legumes (especially lentils), asparagus, avocado, beets, broccoli, Brussels sprouts, papaya, citrus fruit, and leafy greens.
- Test your blood folate level (and ideally all of your B vitamins) to see if you're getting enough from your diet.
- Test all of the genes in your folate cycle (about 5 genes), and ideally also in your methylation cycle (about 5 more genes), and nutrient transport genes, to spot which of your genes might need extra support to run the folate and methylation cycles and other biological processes that require nutrients that you might not absorb well.
- Don't just bypass MTHFR (and other enzymes) by supplementing with methylfolate when you can usually "fix" an MTHFR issue with B2 (riboflavin), best taken in its R5P form.
And if you got value from this email, reply with the word "value".
Share this newsletter (and two free gifts) ... if you know anybody who would get value from these emails, send them to this page to join this newsletter and receive two free gifts worth almost $200.
The next email will cover how to find hidden clues in your Comprehensive Metabolic Panel,
And then we need to talk about a few issues with B6 supplementation because somewhat like folate, B6 can be a "double-edged sword", causing problems for some people if they take too much.
See 'ya in the next email
Kory and Marik were just stripped of their specialty board certifications. So was I, but the ABIM never even bothered to tell me.
Kory and Marik were just stripped of their specialty board certifications. So was I, but the ABIM never even bothered to tell me.
It has been a hard lesson that so many respectable organizations and doctors turned out to be mendacious crooks. But now we know.
merylnass.substack.com
Study shows washing produce does not remove pesticides:
amp.theguardian.com
Peel those apples: washing produce doesn’t remove pesticides, study finds | Pesticides | The Guardian
Another report found pesticide levels posing ‘significant risks’ in 20% of tested fruits and vegetables
US Military backs off proposal to invest in lab grown meat after industry condemnation.
Why would the Department of Defense be involved in this anyway?
US military backs off lab meat proposal after industry condmenation - Beef Central
America's cattle industry says the country’s Department of Defence has walked back a proposal to invest in the development of lab grown meat – after producers and the industry’s peak body condemned the proposal...Read More
www.beefcentral.com
Why would the Department of Defense be involved in this anyway?
That's why I always say grow all that you can yourselfStudy shows washing produce does not remove pesticides:
Peel those apples: washing produce doesn’t remove pesticides, study finds | Pesticides | The Guardian
Another report found pesticide levels posing ‘significant risks’ in 20% of tested fruits and vegetables
It's just par with everything else goin on in the world todayUS Military backs off proposal to invest in lab grown meat after industry condemnation.
US military backs off lab meat proposal after industry condmenation - Beef Central
America's cattle industry says the country’s Department of Defence has walked back a proposal to invest in the development of lab grown meat – after producers and the industry’s peak body condemned the proposal...Read Morewww.beefcentral.com
Why would the Department of Defense be involved in this anyway?
Study shows washing produce does not remove pesticides:
Peel those apples: washing produce doesn’t remove pesticides, study finds | Pesticides | The Guardian
Another report found pesticide levels posing ‘significant risks’ in 20% of tested fruits and vegetables
These are things people BETTER be aware of, come on wake up people or you'll be eatin Bug burgers or lab grown meats, doesn't that sound natural and delicious. They must think they are God.US Military backs off proposal to invest in lab grown meat after industry condemnation.
US military backs off lab meat proposal after industry condmenation - Beef Central
America's cattle industry says the country’s Department of Defence has walked back a proposal to invest in the development of lab grown meat – after producers and the industry’s peak body condemned the proposal...Read Morewww.beefcentral.com
Why would the Department of Defense be involved in this anyway?
WHO exposed as industry puppet by its proposed PFAS drinking water guidelines, forced to redo them
WHO exposed as industry puppet by its proposed PFAS drinking water guidelines, forced to redo them
Improved health, reduced pollution and equity are important values, but the WHO doesn't give them a hoot, ultimately. The World Hellth Organization worked to increase drinking water pollution.
merylnass.substack.com
When guano was gold
When guano was gold
or Poop Makes the World Go Round. From our DoorToFreedom weekly newsletter
merylnass.substack.com
The Japanese monkeypox vaccine
The Japanese monkeypox vaccine
Thoughts on the monkeypox vaccine program and what is the actual cause of death in this generally very mild illness?
merylnass.substack.com
Did you miss our recent webinar on misconceptions about fruit? Would you like to see it presented live?
We invite you to join us for our free webinar Misconceptions About Fruit! This webinar is scheduled for today:
Thursday, August 15th, 2024 at 6 PM Pacific Time (9 PM Eastern Time)
(Friday, August 16th 8 AM Bangkok, 10 AM Tokyo, 11 AM Sydney, 1 PM Auckland)
This is the third in our 2024 Summer Webinar Series! As with all our webinars, this one will contain well-thought-out slides so you can follow along with the subjects we are covering for added clarity. At the end, we'll be there to answer questions on the webinar topic.
Click here to register for this free webinar
In this webinar, you'll learn:
We invite you to join us:
https://event.webinarjam.com/register/88/542nzik1
Healthfully yours,
We invite you to join us for our free webinar Misconceptions About Fruit! This webinar is scheduled for today:
Thursday, August 15th, 2024 at 6 PM Pacific Time (9 PM Eastern Time)
(Friday, August 16th 8 AM Bangkok, 10 AM Tokyo, 11 AM Sydney, 1 PM Auckland)
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This is the third in our 2024 Summer Webinar Series! As with all our webinars, this one will contain well-thought-out slides so you can follow along with the subjects we are covering for added clarity. At the end, we'll be there to answer questions on the webinar topic.
Click here to register for this free webinar
In this webinar, you'll learn:
- How fructose is utilized by the human body. Is it all converted to fat?
- The metabolic differences between fructose and high fructose corn syrup.
- The glycemic index of popular fruits. Is all fruit high glycemic?
- How eating fruit can affect certain lab values, including triglycerides.
- Why knowing this information is important for your health!
We invite you to join us:
https://event.webinarjam.com/register/88/542nzik1
Healthfully yours,
Curious about a fitness secret that keeps top athletes and celebrities, including Serena Williams and Morgan Freeman, in top shape?
Learn about the simple technique they trust to enhance their immune system, strength, flexibility, and overall health.
Dive into the full article and unlock the secret to transforming your health!
Learn about the simple technique they trust to enhance their immune system, strength, flexibility, and overall health.
Dive into the full article and unlock the secret to transforming your health!
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One of our core beliefs at Food Matters is that food is medicine.
We've seen the power of it time and time again. One of our favorite stories of food as medicine comes from our friend Chris Wark, who healed from cancer. Chris has been researching cancer non-stop since he became cancer free 20 years ago... what’s causing cancer, foods that fight cancer, foods that promote cancer growth... He’s researched nearly every natural non-toxic therapy out there. Now, he's sharing some of his favorite anticancer recipes.
CLICK HERE to get the Anticancer Recipes eBook. >>
This recipe eBook features the food he ate during his healing journey, along with some newer recipes that he enjoys today.
The truth is simple - eating whole foods from the earth gives your body vital nutrients that support healing and preventing cancer. The food on the end of your fork has the power to promote health or promote disease.
These recipes are jam packed with cancer-fighting nutrients that help nourish healthy cells, eliminate cancer cells, detoxify your body, and strengthen your immune system.
Access the eBook HERE. >>
In good health,
We've seen the power of it time and time again. One of our favorite stories of food as medicine comes from our friend Chris Wark, who healed from cancer. Chris has been researching cancer non-stop since he became cancer free 20 years ago... what’s causing cancer, foods that fight cancer, foods that promote cancer growth... He’s researched nearly every natural non-toxic therapy out there. Now, he's sharing some of his favorite anticancer recipes.
CLICK HERE to get the Anticancer Recipes eBook. >>
This recipe eBook features the food he ate during his healing journey, along with some newer recipes that he enjoys today.
The truth is simple - eating whole foods from the earth gives your body vital nutrients that support healing and preventing cancer. The food on the end of your fork has the power to promote health or promote disease.
These recipes are jam packed with cancer-fighting nutrients that help nourish healthy cells, eliminate cancer cells, detoxify your body, and strengthen your immune system.
Access the eBook HERE. >>
In good health,
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| Diet Beats Pharmaceuticals for IBS Symptoms in Landmark Clinical Study |
| In a world where prescription pads often take precedence over shopping lists, a surprising revelation has emerged from the realm of irritable bowel syndrome (IBS) research. A groundbreaking study has shed light on the remarkable power of dietary changes in alleviating the relentless abdominal discomfort and erratic bowel habits that plague millions of IBS sufferers worldwide. Brace yourselves for a gut-wrenching twist: could the key to conquering this complex disorder be found not in a pill bottle, but rather on your dinner plate? |
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| mRNA Nanotech Nightmare: Long-Term Study Uncovers Bizarre Vaccine Phenomena |
| Scientists watched for a year as vaccine samples transformed before their eyes. |
Hey Jimi,
If you’ve got an extra bounty of vegetables, what can you do with them? Simple Summer Succotash!
What grows together, goes together; look no further than southern succotash for the proof.
Sweet corn, juicy tomatoes, and toothsome lima beans are the essentials that make up this summertime staple, with plenty of room for creative adaptation.
Get the Simple Summer Succotash HERE
Enjoy!
If you’ve got an extra bounty of vegetables, what can you do with them? Simple Summer Succotash!
Sweet corn, juicy tomatoes, and toothsome lima beans are the essentials that make up this summertime staple, with plenty of room for creative adaptation.
Get the Simple Summer Succotash HERE
Enjoy!
| Hi Jimi, |
| If you’re considering starting an online business that makes the world a better place… |
| Or if you already have one and you want to grow it… |
| This email might be a game-changer. |
| My good friend Jeff Walker is about to host his annual Launch Masterclass™. |
| This is one of the best online launch training courses in the world — and it’s totally free. |
| In the 2024 Launch Masterclass, Jeff will show you what you need to know to start and grow your online business, including how to create and sell your course, product, service, coaching, or membership site. |
| And this year, he’ll show you how AI can be a critical part of your success path (and how it can help you deliver better quality content more efficiently — and break through whatever blocks you might be facing). |
| >> Jeff’s 2024 Launch Masterclass is completely free. You can register here. |
| Jeff is a friend of mine and the New York Times best-selling author of Launch. He practically invented a whole new online business style rooted in generosity, trust-building, and deep service. |
| Jeff’s clients have generated more than a billion dollars in sales. He’s also been a hugely important advisor to FRN and helped us to grow to make the difference we’re making. |
| He only launches this free Masterclass once per year. So now's the time. |
| >> Click this link to join in now. |
| Yours for making a living and making a difference, |
| Ocean Robbins |
| P.S. In spite of — or perhaps even because of — the many problems our world is facing, millions of people are rising up and creating careers that respond to the needs of our times and seek to improve the health of people and the planet. Many of these visionary changemakers are seeking to build businesses online, and they are turning to Jeff Walker for guidance. If this interests you, his upcoming free training series is not to be missed. He only offers it once each year, and it’s about to start. Click here if you want to find out more and join in. |
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Are you getting enough Vitamin D? Most of us aren’t, and it's causing serious health issues.
Even in the summer, you can still be deficient in Vitamin D.
This is because using sunscreen, spending time indoors, and living in areas with high pollution can block the sun's rays, which are essential for Vitamin D production.
And let’s be honest, 1-2 weeks of vacation is not enough to get you out of the office and in the sun (if you’re lucky enough to get vacation at all).
This deficiency matters because Vitamin D is crucial for:
Your hair & skin can suffer too, with dryness,itching, hair loss, and skin conditions like eczema or psoriasis.
Adjusting Vitamin D levels can leave you feeling happier, more energized, and less anxious. You’ll have stronger bones, improved sleep, and newfound motivation fast – in as little as 7 days….
Your immune system will thank you, and you’ll notice more hydrated skin, weight loss, and even new hair growth.
Even in the summer, you can still be deficient in Vitamin D.
This is because using sunscreen, spending time indoors, and living in areas with high pollution can block the sun's rays, which are essential for Vitamin D production.
And let’s be honest, 1-2 weeks of vacation is not enough to get you out of the office and in the sun (if you’re lucky enough to get vacation at all).
This deficiency matters because Vitamin D is crucial for:
- Bone Health
- Immune Function
- Mood Regulation
- Hormonal Balance
- Skin Health
Your hair & skin can suffer too, with dryness,itching, hair loss, and skin conditions like eczema or psoriasis.
Adjusting Vitamin D levels can leave you feeling happier, more energized, and less anxious. You’ll have stronger bones, improved sleep, and newfound motivation fast – in as little as 7 days….
Your immune system will thank you, and you’ll notice more hydrated skin, weight loss, and even new hair growth.
Breast cancer surgery might trigger metastasis, researchers discover why
Breast Cancer Risk Increases After Surgery | NaturalHealth365
(NaturalHealth365) Breast cancer surgery may increase metastasis risk, study suggests. Understand the risks before consenting to mastectomy.
www.naturalhealth365.com
Stress affects gut health in unexpected ways, study suggests
Stress And Your Gut: Microbiome Under Attack | NaturalHealth365
(NaturalHealth365) New research reveals how everyday stress impacts gut health through unexpected changes in the microbiome.
www.naturalhealth365.com
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Real-Time Self-Assembly of Stereomicroscopically Visible Artificial Constructions in Incubated Specimens of mRNA Products Mainly from Pfizer and Moderna: A Comprehensive Longitudinal Study
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Essential Pesticides as Bad as Smoking? Now Linked to 6 Cancers We know pesticides on fruits and vegetables can affect our health, which is why it’s important to buy organic and clean our produce well. Yet, what researchers have found is that in areas where pesticide-laden crops are grown, entire communities are put at higher risk of developing certain types of cancers. For this study published in Frontier in Cancer Control and Society, researchers looked at data from communities throughout the country to compare data between pesticides tracked by the US Geological Survey and the incidence of cancer. They also looked at other potential variables, including cigarette smoking. What the researchers found is that there’s a significant link between pesticide exposure and a higher incidence of several cancers, including leukemia, non-Hodgkin's lymphoma, and cancers of the bladder, colon, lung, and pancreas. For some cancers, the risk associated with pesticide exposure is comparable to smoking. The Many Health & Anti-Aging Benefits of Rosehips Rosehips might be small, but these amazing “fruits” are packed with incredible health benefits that few people know about. Coming from the familiar rose plant, rosehips form after the flowers die and can be seen clearly when the petals drop. Rosehips are a little-known source of vitamin C, packing more of this nutrient than most fruits and vegetables. Plus, they are filled with other potent antioxidants like polyphenols, flavonoids, carotenoids, and vitamin E. While antioxidants have many protective roles to play in your body, one of the biggest is helping to lower chronic inflammation, which can contribute to a wide range of chronic diseases. Studies show there could be significant health benefits of rosehips for arthritis—namely easing pain and inflammation. One reason is that rosehips contain compounds known as galactolipids which are being researched because of their powerful anti-inflammatory properties and likely play a large role in easing arthritis symptoms. Plus, rosehips help to protect gut health, support a healthy heart, and may have incredible anti-aging benefits for the skin. |
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| NEW Episode of the HEAL with Kelly Podcast - The Luminous Self: Sacred Yogic Practices and Rituals to Remember Who You Are with Tracee Stanley |
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| In this beautiful episode of the HEAL with Kelly Podcast, I speak with Tracee Stanley, a teacher with over 28 years of wisdom in Sri Vidya Tantra, and the author of 'Radiant Rest' and 'The Luminous Self.' Together we discuss the power of surrender, the transformative benefits of yoga, and the impact of yogic philosophy on daily living. Tracee shares a number of profound insights on finding joy and connection in our modern lives while emphasizing the importance of intentional rest to counteract our collective culture of urgency. We also explore the depths of Yoga Nidra, known as the yoga of sleep, and discover how it can lead to profound peace and bliss. We later delve into the illusion of separation and why it's critical for us to recognize our interconnectedness with nature, our environment, and all living beings. Tracee also shares her personal journey of overcoming fear, discovering joy as an intrinsic part of being, balancing joy and sorrow, and finding clarity through unwinding psychic knots. She emphasizes the importance of reconnecting with our inner truth amidst an overwhelming amount of distractions and reflects on how we can turn past traumas into empowerment. Tune into this transformational episode now for powerful insights and practices to help you navigate your personal journey and find deeper connection and joy in your life. |
gopher_byrd
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Member For 5 Years
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It's just a freaking cold. Enough with the Wuhan flu already...
| The Age of Autoimmune: Unraveling Our Modern Health Crisis with Dr. Will Cole |
|
| In this nugget from last week's episode of the HEAL with Kelly Podcast, Dr. Will Cole tackled what many are referring to as 'The Age of Autoimmune,' highlighting the alarming rise of autoimmune diseases that now stand as a major concern in our health landscape. Dr. Cole stresses the importance of recognizing how closely our bodies and environments are linked, advocating for functional medicine's holistic methods as an effective way to tackle these root issues. His insights compel us to rethink our health practices, pushing for a comprehensive approach that aligns with our natural biological processes to address this escalating health crisis. For an in-depth exploration of these topics and more insights from Dr. Cole, click the button below. |
| You can also watch the full podcast episode with Dr. Will Cole on YouTube by CLICKING HERE, or listen to it now on either SPOTIFY or APPLE. |
as long as people have an imagination, therewill be new diseases around.
The Age of Autoimmune: Unraveling Our Modern Health Crisis with Dr. Will Cole
In this nugget from last week's episode of the HEAL with Kelly Podcast, Dr. Will Cole tackled what many are referring to as 'The Age of Autoimmune,' highlighting the alarming rise of autoimmune diseases that now stand as a major concern in our health landscape. Dr. Cole stresses the importance of recognizing how closely our bodies and environments are linked, advocating for functional medicine's holistic methods as an effective way to tackle these root issues. His insights compel us to rethink our health practices, pushing for a comprehensive approach that aligns with our natural biological processes to address this escalating health crisis. For an in-depth exploration of these topics and more insights from Dr. Cole, click the button below.
You can also watch the full podcast episode with Dr. Will Cole on YouTube by CLICKING HERE, or listen to it now on either SPOTIFY or APPLE.
Breath meditation: A great way to relieve stress
Breath meditation: A great way to relieve stress - Harvard Health
Mindfulness-based meditation helps to control stress and preserve health. It combines rhythmic breathing and focused attention. It is a form of entry-level meditation that anyone can do. It brings ...
www.health.harvard.edu
The Truth About Vaccine Lies: How the Unvaccinated Protect Our Communities
The Truth About Vaccine Lies: How the Unvaccinated Protect Our Communities
Understanding the Misconceptions Surrounding Vaccine Safety and Effectiveness
kidsfirst4ever.substack.com
Corrected: International Crisis Summit in Tokyo, Sept 24-28
Corrected: International Crisis Summit in Tokyo, Sept 24-28
What a great way to share what we know and establish a global network
merylnass.substack.com
WHO monkeypox data dated Aug 12 not worrisome.
WHO monkeypox data dated Aug 12 not worrisome.
On June 30 there had only been 208 reported deaths during the past 2.5 years
merylnass.substack.com
Roguski wrote (5 minutes ago) that the UN's Declaration on Future Generations needs to be rejected officially by 4 pm tomorrow. If so, I had already highlighted areas of concern so will publish now
Roguski wrote (5 minutes ago) that the UN's Declaration on Future Generations needs to be rejected officially by 4 pm tomorrow. If so, I had already highlighted areas of concern so will publish now
Even though I originally intended to add comments
merylnass.substack.com
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The latest research on plant-based nutrition including which foods have been shown to prevent and even reverse disease.